Decrease of Recurrent Pancreatitis

Tampere University

Status: Completed

Conditions: Pancreatitis

Treatments: Behavioral: Repeated behavioural intervention without any drugs

Study type: Interventional

Funder types: Other

Identifiers

NCT00534534

R00126A

Details and patient eligibility

About

Retrospective studies have shown, that about half of the patients will have a recurrent episode after the first acute alcoholic pancreatitis. Of the patients in hospital, more than half annually are treated for recurrent acute pancreatitis. Because alcohol has been shown an important factor in the development of recurrent pancreatitis, it was hypothesized, that by attempting intensively to diminish the individual alcohol consumption the number of recurrent pancreatitis could be decreased. Two protocols will be compared: A) initial intervention against alcohol abuse and B) repeated interventions at 6 month intervals.

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who recovered from their first acute alcoholic pancreatitis and start to be ready to be discharged from hospital

Exclusion criteria

• Other etiologies of pancreatitis besides alcohol
• Uncertain diagnosis
• Recurrent disease
• Refusal

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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120 participants in 2 patient groups

1

Active Comparator group

Description:

All these patients will be advised, i.e. undergo behavioural intervention, against alcohol use in the standard fashion. No drugs will be used. In addition, they also will undergo repeated similar interventions at 6 mo intervals. They are re-examined at two years for alcohol consumption and for the number of recurrent pancreatitis during the two year period.

Treatment:

Behavioral: Repeated behavioural intervention without any drugs

Standard

No Intervention group

Description:

All these patients will be advised, i.e. undergo behavioural intervention, against alcohol use in the standard fashion. No drugs will be used. They are re-examined at two years for alcohol consumption and for the number of recurrent pancreatitis during the two year period.