Decreased Tongue Strength is Related to Skeletal Muscle Mass in COPD Subjects

Kindai University

Status: Completed

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Diagnostic Test: balloon-based tongue pressure measurement device

Study type: Observational

Funder types: Other

Identifiers

NCT04761380

0414

Details and patient eligibility

About

Background:

Dysphagia is frequently observed in subjects with chronic obstructive pulmonary disease (COPD). But tongue strength has not been investigated yet in COPD subjects. The investigators hypothesized that tongue strength is weaker in COPD subjects compared to normal subjects.

Methods:

This was a single-centre, observational, and cross-sectional study. Twenty-seven subjects with COPD and twenty-four age-matched control subjects were enrolled in this study. Isometric tongue strength was measured using a device fitted with a disposable oral balloon probe. The investigators also evaluated handgrip strength, gait speed, and appendicular skeletal muscle mass (ASM) to define participants as having sarcopenia. ASM, fat free mass index (FFMI), and skeletal muscle mass index (SMI) were measured by bioelectrical impedance analysis. Gait speed was measured using the 6-meter walking test. The eating assessment test-10 (EAT-10) was used to diagnose dysphagia.

Enrollment: 51 patients

Sex: All

Ages: 65+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of stable COPD.
• Age-matched control subjects who did not have any pulmonary disease.

Exclusion criteria

• Participants with metallic implants.
• History of stroke disease.
• History of neuromuscular disease.
• Participants who did not have their front teeth.

Trial design

51 participants in 2 patient groups

stable COPD subjects

Treatment:

Diagnostic Test: balloon-based tongue pressure measurement device

age-matched control subjects subjects who did not have any pulmonary disease

Treatment:

Diagnostic Test: balloon-based tongue pressure measurement device