Deep Brain Stimulation for Patients With Parkinson's Disease. (STTARTLATE)

Institut National de la Santé Et de la Recherche Médicale, France

Status: Completed

Conditions: Parkinson Disease

Treatments: Device: Stimulation of the subthalamic nucleus

Study type: Observational

Funder types: Other

Identifiers

NCT03128567

C 14-01

Details and patient eligibility

About

Deep brain stimulation of the sub thalamic nucleus (STN-DBS) is an efficient treatment to improve motor and non motor signs of Parkinson's disease (PD). In people aged more 70 years, an increased rate of side effects such as post-operative cognitive decline and/or postural instability with falls has been suspected with less improvement in the quality of life. Here, Investigators aim further explore the effects of STN-DBS in 50 patients with PD people aged more 69 years in a randomized parallel controlled study.

Full description

The effects of combined bilateral deep brain stimulation of the subthalamic nucleus and medical treatment on the quality of life will be evaluated in 25 PD patients aged more 69 years in comparison to 25 PD patients aged more 69 years that only received medical drug treatment.

Enrollment: 10 patients

Sex: All

Ages: 69 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Parkinson's disease
• disease duration > 5 years
• levodopa related motor complications
• dopasensitivity > 50%
• signed informed written consent
• medical social insurance

Exclusion criteria

• dementia
• contra-indication to neurosurgery

Trial design

10 participants in 2 patient groups

Stimulation of the subthalamic nucleus

Description:

25 patients with Parkinson's disease

Treatment:

Device: Stimulation of the subthalamic nucleus

Best medical treatment

Description:

25 patients with Parkinson's disease