Deep Brain Stimulation in Patients With Parkinson's Disease

Mayo Clinic

Status: Completed

Conditions: Parkinson's Disease

Treatments: Procedure: Deep brain stimulation surgery.

Study type: Interventional

Funder types: Other

Identifiers

NCT00586079

06-003248

Details and patient eligibility

About

The purpose of this study is to determine the effect of deep brain stimulation surgery on movement-related cortical potentials in patients with Parkinson's disease.

Full description

Patients who have had deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona will have electroencephalographic (EEG) measurements with the stimulator on followed by EEG measurements with the stimulator off. Patients who are scheduled to have deep brain stimulation surgery for Parkinson's disease will have EEG measurements before and after surgery.

Enrollment: 20 patients

Sex: All

Ages: 40 to 82 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who have had deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona, or who are scheduled to have deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona.

Exclusion criteria

• Patients unable to do repetitive dorsiflexion of the wrist due to orthopedic problems.
• Pregnant women.
• Prisoners or institutionalized individuals.

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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20 participants in 2 patient groups

A

Experimental group

Description:

Ten patients who have had deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona.

Treatment:

Procedure: Deep brain stimulation surgery.

B

Experimental group

Description:

Ten patients who are scheduled to have deep brain stimulation surgery for Parkinson's disease at Mayo Clinic Arizona.

Treatment:

Procedure: Deep brain stimulation surgery.