Deep Parasternal Intercostal Plane Block (DPIP)

Institute Arnault Tzanck, France

Status: Completed

Conditions: Nerve Block

Treatments: Procedure: Deep parasternal intercostal plane block

Study type: Interventional

Funder types: Other

Identifiers

NCT06895876

2021-A01183-38

Details and patient eligibility

About

Cardiac surgery is a source of severe post operative pain witch can cause major respiratory complications due to non optimal post operative rehabilitation.

Multimodal analgesia provides acceptable pain control , but does not seem sufficient during coughing or mobilization. The use of morphine also exposes patients to side effects (nausea, vomiting, pruritus, respiratory depression, chronic pain, ileus). Bleeding and hemodynamic risks of peridural and spinal aneshesia limits their use.

The postoperative efficacy of deep parasternal intercostal plane block has not yet been evaluated sufficiently. The aim of this study is to evaluate the efficacity of TTMPB on the quality of postoperative recovery after cardiac surgery.

Enrollment: 128 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients requiring cardiac surgery with sternotomy

Exclusion criteria

• Emergency procedure
• Procedures requiring lateral chest drainage
• Hemodynamic instability
• Severe kidney or liver failure
• BMI > 40
• Chronic pain
• Allergy to local anesthesics
• Pregnant woman
• Long term opioïds use

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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128 participants in 2 patient groups

Deep parasternal intercostal plane block

Experimental group

Description:

The block is performed bilaterally in the 4th intercostal space. The probe is placed in the latero-median axis and a needle is placed latero-medially between the intercostal and transverse thoracic muscle. The solution is then injected under ultrasound control ()20 mL of 0,375% Naropeïne

Treatment:

Procedure: Deep parasternal intercostal plane block

Control

No Intervention group

Description:

Standard multimodal analgesia