Defining Reference Ranges for Cerebral Oxygenation In Neonates (COIN) During Immediate Neonatal Transition After Birth

Medical University of Graz

Status: Completed

Conditions: Neonatal Adaptation

Treatments: Other: No Intervention

Study type: Observational

Funder types: Other

Identifiers

NCT04594824

32-320 ex 19/2

Details and patient eligibility

About

Especially in neonates non-invasive methods are required for monitoring the complex changes during immediate transition after birth to improve assessment of neonate and eventually resuscitation. During this period especially, the brain is vulnerable and monitoring the brain and possible influencing factors of cerebral oxygenation and perfusion are of great interest. To initiate and guide therapies based on cerebral oxygenation, it is important to define reference ranges.

Enrollment: 192 patients

Sex: All

Ages: Under 15 minutes old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Term and preterm neonates observed routinely at the resuscitation desk
• Decision to conduct full life support
• Written informed consent
• Neonates who require no respiratory or medical support

Exclusion criteria

• No decision to conduct full life Support
• No written informed consent
• Congenital malformation
• Neonates who require respiratory and/ or medical support

Trial design

192 participants in 2 patient groups

Term neonates

Treatment:

Other: No Intervention

Preterm neonates

Treatment:

Other: No Intervention