Definition of ARDS in Qinghai Province: Verification of Berlin Definition Plateau Criteria

Southeast University, China

Status: Unknown

Conditions: ARDS; High Altitude

Study type: Observational

Funder types: Other

Identifiers

NCT04199650

ARDS Plateau Criteria

Details and patient eligibility

About

The severity stratification criteria for acute respiratory distress syndrome (ARDS) in Xi'ning Qinghai province (mean altitude: 2200m) were clarified according to the oxygenation index (PaO2/FiO2).

Full description

This study is a single-center retrospective study. According to the Berlin diagnostic standard, ARDS patients admitted to the Department of severe Medicine, affiliated Hospital of Qinghai University from January 2018 to December 2018 were divided into three groups: mild (153mmHg < PaO2/ FiO2 ≥ 230 mmHg), moderate (76mmHg < PaO2/ FiO2 ≥ 153 mmHg) and severe (PaO2/ FiO2 ≥ 76 mmHg). The ICU mortality, 28-day mortality, non-ventilator time in ICU, ICU hospitalization time and non-I hospitalization were observed respectively. The difference of CU time and total hospitalization days.

Enrollment: 253 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of age
• Meet the diagnostic criteria of ARDS
• Receive invasive mechanical ventilation

Exclusion criteria

• Receive a large number of hormone shock therapy in a short period of time
• Death within a short period of time (< 24 h) after mechanical ventilation
• No chest imaging data
• Data missing

Trial design

253 participants in 3 patient groups

Mild ARDS

Description:

153mmHg\<PaO2/FiO2≤230mmHg

Moderate ARDS

Description:

76mmHg\<PaO2/FiO2≤153mmHg

Severe ARDS

Description:

PaO2/FiO2≤76mmHg