Delayed-Enhancement Cardiovascular Magnetic Resonance in Patients With Sarcoidosis

Duke University

Status: Enrolling

Conditions: Sarcoidosis

Study type: Observational

Funder types: Other

Identifiers

NCT01745237

Pro00008224

DCMRC-8224a (Other Identifier)

Details and patient eligibility

About

The primary objective of this study was to determine the ability of cardiac magnetic resonance (CMR) to identify cardiac involvement in patients with sarcoidosis. Patients were to undergo CMR in addition to routine clinical evaluation.

Full description

In patients with sarcoidosis, cardiac death is a leading cause of mortality which may represent unrecognized cardiac involvement. Cardiovascular magnetic resonance (CMR) can detect cardiac involvement including minute amounts of myocardial damage. Therefore, the objective of this study was to determine the usefulness of CMR and compare it with standard clinical evaluation for cardiac involvement. Patients with documented extracardiac sarcoidosis or clinically suspected cardiac sarcoidosis will be enrolled.

Enrollment: 27,000 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Biopsy proven sarcoidosis
• Suspected cardiac sarcoidosis

Exclusion criteria

• Contraindication to MRI