Delayed or Direct Ureteroscopy in the Treatment of Pediatric Calcular Anuria

Cairo University (CU)

Status: Unknown

Conditions: Anuria; Ureteric Stones; Obstructive Uropathy; Acute Renal Failure

Treatments: Procedure: initial urinary drainage; Procedure: direct ureteroscopy

Study type: Interventional

Funder types: Other

Identifiers

NCT02139059

61179

Details and patient eligibility

About

To compare staged ureteroscopy following initial urinary drainage versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure in children.

Full description

To compare staged ureteroscopy following initial urinary drainage and stabilization of renal functions using percutaneous nephrostomy or double J stent versus direct ureteroscopy without initial urinary drainage in the treatment of obstructive calcular anuria with acute renal failure due to ureteric calculi in children.

Enrollment: 50 estimated patients

Sex: All

Ages: Under 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children ≤12 years old presenting with Obstructive Anuria and Acute Renal Failure due to bilateral ureteric stones suitable for ureteroscopy.

Exclusion criteria

• Fever, pyonephrosis or sepsis.
• unstable patients are stabilized first by dialysis.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

initial urinary drainage

Active Comparator group

Description:

initial urinary drainage to stabilize renal functions before ureteroscopy

Treatment:

Procedure: initial urinary drainage

direct ureteroscopy

Active Comparator group

Description:

direct ureteroscopy without initial urinary drainage

Treatment:

Procedure: direct ureteroscopy