Delivery of Self Training and Education for Stressful Situations-Telephone Version (DESTRESS-T)

Uniformed Services University (USU)

Status: Unknown

Conditions: PTSD

Treatments: Behavioral: DESTRESS-T; Other: Optimized Usual Care (OUC)

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT01502449

D10-I-AR-J5-786

Details and patient eligibility

About

This study will evaluate a telephone-delivered cognitive-behavioral psychotherapy intervention designed for primary care treatment of combat-exposed service members with PTSD. The investigators will assess Posttraumatic Stress Disorder (PTSD) symptoms, mental health-related and occupational functioning, and symptoms of depression, anxiety, and somatization.

Full description

This is a randomized controlled trial that will compare DESTRESS-T to Optimized Usual Care (OUC). Optimized Usual Care is usual primary care PTSD treatment, plus a telephone care management program that includes: four outreach calls, feedback to the treating primary care provider (PCP), and care coordination.

Enrollment: 91 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age>18 years
• DSM-IV diagnosis of PTSD (derived from the CAPS) due to combat in OIF/OEF deployment
• Active duty personnel

Exclusion criteria

• Active suicidal or violent ideation within the past two months as assessed by the MINI and a supplementary form developed by the project team (see Appendices)
• Current participation in any active psychotherapy (e.g., psychoanalysis, CBT) for mood, anxiety or substance use disorders (as determined via service member self report and/or check of medical record)
• Recurrent PTSD treatment failure in psychotherapy, as determined via consensus of study team members (Dr. Charles Engel, Dr. Brett Litz, and Dr. Kristie Gore)
• Current alcohol dependence, as assessed by MINI
• Acute psychosis, psychotic episode, or psychotic disorder diagnosis within the past year, as assessed by the MINI
• Currently on an antipsychotic or mood-stabilizing agent for bipolar disorder or any disorder with psychotic features, as determined by medical record and/or self report
• Unstable administration schedule or dosing of any antidepressant, anxiolytic, or sedative-hypnotic (i.e., will exclude for any related medication changes in the month prior to randomization), as determined by medical record or service member self report
• Acute or unstable physical illness based on the judgment of the patient's primary care clinician and the study team.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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91 participants in 2 patient groups

DESTRESS-T

Experimental group

Description:

Usual primary care PTSD treatment, plus a telephone care management program over 8 weeks that includes: four outreach calls, feedback to the treating primary care provider, and care coordination

Treatment:

Behavioral: DESTRESS-T

Optimized Usual Care (OUC)

Active Comparator group

Description:

Optimized Usual Care is usual primary care PTSD treatment, plus a telephone care management program that includes: four outreach calls, feedback to the treating primary care provider (PCP), and care coordination.

Treatment:

Other: Optimized Usual Care (OUC)