Delphi Consensus Excessive Daytime Sleepiness in OSA

King's College London

Status: Completed

Conditions: Obstructive Sleep Apnea

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT05055271

2021 EDS in OSA Delphi V1.0

Details and patient eligibility

About

The objective of this study is to generate expert consensus statements on the differential diagnosis, definition, and management of EDS in patients with OSA who are adequately treated with primary therapy.

Full description

A study will be performed using a modified Delphi process with an international expert panel to generate recommendation statements related to the differential diagnosis and management of patients with residual EDS in OSA (and relevant sub-topics) and to determine the level of agreement for each statement from the panel as a whole. The following topics will be covered:

1. EDS: definition, evaluation/assessment, and tools
2. Definitions of residual EDS in patients with OSA treated with primary OSA therapy
3. Practical recommendations
4. Management Consensus is achieved through iterative rounds of survey and revision to the statements until a pre-determined level of agreement is met (80% agreement).

Part 1: planning and evidence review

• Series of planning sessions with co-chairs and faculty leads
• Literature is reviewed/summarized
• Initial statements will be developed based on evidence Recommendation statements on EDS in OSA will be formulated and rated according to level of agreement on a 5-point Likert scale.

Part 2: Survey to achieve consensus

• Survey, based on the initial statements developed by faculty leads, will be developed to allow for vetting by full faculty group
• At least 3 rounds of review (2 remote and 1 live [virtual]) will be held to achieve consensus on each topic of interest and finalize consensus statements

Enrollment: 10 patients

Sex: All

Ages: 19+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Members of the panel include experts in sleep and respiratory medicine in North American and Europe.

Exclusion criteria

• Panelists who were not able to commit to all rounds of the modified Delphi process will be excluded.

Trial design

10 participants in 1 patient group

Delphi panel

Description:

The Delphi panel will include 10 international experts in sleep and respiratory medicine. Two panelists will serve as co-chairs and eight panelists will serve as section leads for the major topic areas throughout the process. A series of planning sessions will be conducted with the co-chairs and section leads prior to implementation of the survey.