Demographics and Clinical Characteristics of Ocular Inflammatory Diseases in Singapore

Singapore National Eye Centre

Status

Active, not recruiting

Conditions

Uveitis

Endophthalmitis

Masquerade Syndromes

Scleritis and Episcleritis

Intraocular Lymphoma

Treatments

Other: No Intervention: Observational Cohort

Study type

Observational

Funder types

Other

Identifiers

NCT07176130

2019/2811

Details and patient eligibility

About

This is a retrospective study analyzing demographics, clinical characteristics, treatment received, and outcomes of ocular inflammatory diseases that presented to the Singapore National Eye Centre (SNEC).

Full description

This is a retrospective, cross-sectional study. In this study, the investigators aim to investigate demographics, clinical characteristics, treatment received, and outcomes of ocular inflammatory diseases, including masquerade syndromes such as ocular neoplasms (e.g., vitreoretinal and uveal lymphoma) and endophthalmitis that presented to the Singapore National Eye Centre (SNEC). Data on demographics, clinical features, diagnosis, investigations, secondary complications, treatment received, and outcomes will be analyzed using statistical software. The results of this study will lead to an improved clinical practice with better treatment selections and an optimized monitoring protocol for follow-up care for patients with ocular inflammatory diseases, including masquerade syndromes such as ocular neoplasms (e.g.,vitreoretinal and uveal lymphoma) and endophthalmitis. This will lead to better clinical outcomes and prevention of serious sight-threatening complications.

Enrollment

200 estimated patients

Sex

All

Ages

21 to 99 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients diagnosed with uveitis
Patients diagnosed with scleritis or episcleritis
Patients diagnosed with ocular neoplasms e.g., vitreoretinal and uveal lymphoma
Patients diagnosed with endophthalmitis
Diagnosis confirmed by laboratory testing or histopathological examination
Patients diagnosed and managed at the Singapore National Eye Centre (SNEC)

Exclusion criteria

Patients with less than two years of clinical follow-up
Patients with incomplete diagnostic confirmation (i.e., lacking laboratory or histopathological evidence)
Patients diagnosed outside of Singapore National Eye Centre (SNEC)
Cases with missing key clinical or outcome data