Demographics, Diagnosis, Management, and Outcomes of Non-occlusive Mesenteric Ischemia.

University of Tartu

Status: Active, not recruiting

Conditions: Non-Occlusive Mesenteric Ischemia

Treatments: Other: No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06970015

NOMI-AMESI

Details and patient eligibility

About

This prospective multicenter observational study, conducted between June , 2022, and April, 2023, is a preplanned analysis of the AMESI study titled 'Demographics, diagnosis, management, and outcomes of non-occlusive mesenteric ischemia,' aiming primarily to describe the demographic profile, clinical presentation, and laboratory findings of patients with non-occlusive mesenteric ischemia (NOMI), and secondarily to identify independent risk factors as well as diagnostic approaches, management strategies, and outcomes-including in-hospital, 90-day, and one-year results.

Enrollment: 566 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

All at least 18-year-old patients with acute mesenteric ischemia or patients suspected of acute mesenteric ischemia that was not confirmed

• Patients with arterial occlusive AMI
• Patients with non-occlusive mesenteric ischemia
• Patients with venous occlusive AMI
• Patients with unclear mechanism of AMI
• Patients with suspected but not confirmed AMI

Exclusion criteria

• Patients with other specific form of AMI (e.g dissection)
• Confirmed strangulating bowel obstruction
• Individuals under 18 years of age.
• Consent declined by patient or next of kin
• Chronic mesenteric ischaemia without an acute event

Trial design

566 participants in 5 patient groups

Patients with non-occlusive mesenteric ischemia

Description:

Patients with non-occlusive mesenteric ischemia, n=55

Treatment:

Other: No intervention

Patients with arterial occlusive mesenteric ischemia

Description:

Patients with arterial occlusive mesenteric ischemia, n=231

Treatment:

Other: No intervention

Patients with venous occlusive mesenteric ischemia

Description:

Patients with arterial occlusive mesenteric ischemia, n=73

Treatment:

Other: No intervention

Patients with unclear mechanism of acute mesenteric ischemia

Description:

Patients with unclear mechanism of acute mesenteric ischemia, n=48

Treatment:

Other: No intervention

Patients with suspected but not confirmed acute mesenteric ischemia

Description:

Patients with suspected but not confirmed acute mesenteric ischemia, n=159

Treatment:

Other: No intervention