Demonstrate Exubera Works As Well As Avandia When Added To Sulfonylurea + Metformin In Controlling Glucose

Pfizer

Status and phase: Completed; Phase 3

Conditions: Diabetes Mellitus

Treatments: Drug: Inhaled insulin

Study type: Interventional

Funder types: Industry

Identifiers

NCT00150410

A2171017

Details and patient eligibility

About

• Whether a combination of three therapies - metformin and a sulfonylurea plus Exubera, an investigational drug, controls your diabetes at least as much as a triple combination therapy of metformin and a sulfonylurea plus Avandia, a Food and Drug Administration (FDA) approved drug.
• Whether a combination of two therapies - metformin plus Exubera controls your diabetes at least as much as a as a triple combination therapy of metformin and a sulfonylurea plus Avandia.

Enrollment: 626 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type 2 diabetes
• Currently treated and on a stable doses of drugs for the preceding two (2) months

Exclusion criteria

• Type 1 Diabetes
• Smoking

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)