Dendritic Cells-Derived Exosomes in Human Sepsis

Jinling Hospital, China

Status: Unknown

Conditions: Sepsis

Treatments: Drug: Antibiotics

Study type: Observational

Funder types: Other

Identifiers

NCT02957279

20161103

Details and patient eligibility

About

The amount of peripheral blood exosomes has been confirmed to change in the endotoxin-induced infection. The primary objectives of this study are to compare the changes of peripheral blood dendritic cell-derived exosomes in the patients with sepsis and the healthy controls.

Full description

This is a prospective, single-centered, clinical cohort study.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients were selected with the diagnostic standard "Sepsis 3.0".
• Healthy volunteers do not have serious illness.

Exclusion criteria

• Patients or volunteers do not agree to provide written informed consent and / or can not be legally authorized to provide informed consent.
• Patients give up treatments.
• Patients or volunteers withdrew from the study.

Trial design

50 participants in 2 patient groups

Sepsis group

Description:

The patients were admitted to the Jinling Hospital, who met the diagnosis of sepsis(Sepsis 3.0).

Treatment:

Drug: Antibiotics

Healthy control group

Description:

Healthy volunteers.