Dental Care and Initiation of Anti-osteoporotic Therapy

Centre Hospitalier Universitaire de Nice

Status: Completed

Conditions: Osteoporosis; Dental Condition

Treatments: Drug: biphosphonates; Procedure: Dental care

Study type: Observational

Funder types: Other

Identifiers

NCT05719818

22Rhumato04

Details and patient eligibility

About

The initiation of bisphosphonate therapy for osteoporosis requires an assessment of the oral status to prevent the risk of osteonecrosis of the jaw. This recommendation is sometimes a hindrance to the initiation of treatment or may be responsible for a delay in treatment or even the failure to initiate treatment. However, in the case of a severe osteoporotic fracture (femoral or humeral neck fracture, vertebral fracture or pelvic fracture), treatment must be rapid because of the major risk of refracture in the short term (multiplied by 5 in the 2 years following the fracture).

In the rheumatology department of the Nice University Hospital, the investigator team take care of patients with osteoporotic fractures either directly in hospital or referred by the orthopedics department as part of a care program. For these patients, the team perform an etiological assessment, bone densitometry and evaluation of the oral status with dental panoramic and tele-expertise to determine if there is an indication to perform surgical care before starting the treatment.

Therefore, the investigator aimed to describe the number of patients requiring dental surgery befor the initiation of bisphosphonate or denosumab treatment before to introduce treatment for osteoporosis

Enrollment: 338 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• osteoporotic fracture requiring treatment with bisphosphonate or denosumab

Exclusion criteria

• osteoporotic fracture requiring teriparatide treatment

Trial design

338 participants in 2 patient groups

Treatment initiation

Description:

patients with a satisfactory oral assessment authorizing the immediate prescription of treatment.

Treatment:

Drug: biphosphonates

Surgical dental care

Description:

patients requiring surgical dental care before treatment initaition.

Treatment:

Procedure: Dental care