Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia (SMILE)

Toulouse University Hospital

Status: Not yet enrolling

Conditions: Dental Diseases

Treatments: Other: Questionnaires

Study type: Observational

Funder types: Other

Identifiers

NCT06506734

RC31/23/0443

Details and patient eligibility

About

The main objective of this study is to assess the prevalence of dental discoloration (dental dyschromia) in children who experienced high levels of bilirubin in their blood (hyperbilirubinemia) during their early years. The study will also examine risk factors associated with this condition, such as the duration and severity of hyperbilirubinemia, underlying diseases, and treatments received.

The researchers hypothesize that the quality of life of individuals with dental dyschromia is lower than that of individuals without dyschromia. The results of this study will be used to discuss coverage for dental care with health insurance for children affected by this condition.

Enrollment: 120 estimated patients

Sex: All

Ages: 12 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• A patient with biliary atresia, progressive familial intrahepatic cholestasis, or Alagille syndrome
• Patient or legal representative not opposed to participating in this research.

Exclusion criteria

• Inability to understand and respond to quality of life questionnaires

Trial design

120 participants in 1 patient group

Dental Dyschromia in Hyperbilirubinemia Patients

Description:

30 minutes

Treatment:

Other: Questionnaires