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Depression Prevention Program for Adolescents

The University of Texas System (UT) logo

The University of Texas System (UT)

Status

Completed

Conditions

Depression

Treatments

Behavioral: Bibliotherapy
Behavioral: Supportive/expressive (S/E) therapy
Behavioral: Cognitive behavior therapy (CBT)

Study type

Interventional

Funder types

Other
NIH

Identifiers

NCT00183417
DSIR 84-CTP
R01MH067183 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study will compare the effectiveness of two programs designed to prevent depression in adolescents.

Full description

Major depression is one of the most common psychiatric disorders in adolescents. In many cases, the condition is recurrent and can result in serious psychological impairment. A high number of depressed adolescents never receive treatment; therefore, it is crucial to develop prevention programs for this disorder that are effective and can be easily disseminated. This study will evaluate and compare the effectiveness of cognitive behavior therapy (CBT) and supportive/expressive (S/E) therapy in preventing depressive symptoms in adolescents.

This study will last 2 years. Participants will be randomly assigned to receive six sessions of CBT, S/E therapy, or standard depression education over 2 years. The CBT intervention will focus on reducing negative thoughts and increasing engagement in pleasant activities. S/E therapy is designed to allow adolescents to express their negative emotions and talk about recent stressful events in a supportive environment of their peers. Surveys and psychiatric interviews will be completed by all participants and their parents at the beginning and the end of the study. The surveys and interviews will assess depressive symptoms.

Enrollment

350 patients

Sex

All

Ages

14 to 18 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Beck Depression Inventory score higher than 10
  • Parent or guardian willing to provide informed consent

Exclusion criteria

  • Diagnosis of depression

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

350 participants in 4 patient groups

1
Experimental group
Description:
Participants will receive cognitive behavioral therapy
Treatment:
Behavioral: Cognitive behavior therapy (CBT)
2
Active Comparator group
Description:
Participants will receive supportive/expressive therapy
Treatment:
Behavioral: Supportive/expressive (S/E) therapy
3
Active Comparator group
Description:
Participants will receive bibliotherapy
Treatment:
Behavioral: Bibliotherapy
4
No Intervention group
Description:
Participants in the control condition will receive no treatment

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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