Dermabrasion in Mohs: Split-Scar Trial

University of Wisconsin (UW)

Status: Enrolling

Conditions: Wound Heal

Treatments: Procedure: Dermabrasion

Study type: Interventional

Funder types: Other

Identifiers

NCT07213921

A534300 (Other Identifier)

2025-0592

Protocol Version 3/21/25 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to determine the potential influence of intraoperative dermabrasion on scars following Mohs Micrographic Surgery (MMS). Researchers are trying to determine if dermabrasion, a method to gently remove the top layer of your skin, is a good or bad tool to improve scar appearance after healing. The use of dermabrasion technique in this study is considered investigational. 50 participants will be enrolled and on study for up to 6 months.

Full description

Primary Objective: Scar assessment at 3 months postoperatively by utilizing observer component of Patient and Observer Scar Assessment Scale (POSAS)

Secondary Objectives:

• Patient portion of POSAS
• Overall patient opinion of scar appearance
• Complication rate

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Able to give informed consent themselves
• Scheduled for cutaneous surgical procedure on the face or neck with predicted linear closure greater than 4 centimeters.
• Willing to return for follow up visit within the evaluation period

Exclusion criteria

• Patients with impaired decision-making capacity
• Significant vision or hearing impairments
• Pregnant Individuals
• Incarceration
• Wounds with predicted closure length less than 4 cm

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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50 participants in 2 patient groups

A: Superior Side of the Wound

Experimental group

Description:

The participant's wound will be labeled A if it is on the left or superior side of the investigator

Treatment:

Procedure: Dermabrasion

B: Inferior Side of the Wound

Experimental group

Description:

The participant's wound will be labeled B if it is on the right or inferior side of the investigator

Treatment:

Procedure: Dermabrasion