Dermatitis Herpetiformis Refractory to Gluten Free Diet

Tampere University Hospital

Status: Invitation-only

Conditions: Dermatitis Herpetiformis

Treatments: Other: Assessment of prognosis of refractory dermatitis herpetiformis. No intervention

Study type: Observational

Funder types: Other

Identifiers

NCT05998291

R23003

Details and patient eligibility

About

The main purpose of the study is to find out

1. the natural course of refractory dermatitis herpetiformis and the development of possible complications
2. the strictness of gluten-free diet treatment in refractory dermatitis herpetiformis

Full description

Refractory dermatitis herpetiformis refers to dermatitis herpetiformis unresponsive to gluten-free diet therapy. So far, there is very little knowledge on the course of the disease and the causes and prognosis of refractory celiac disease.

Study patients with refractory dermatitis herpetiformis will be recruited. As a control material dermatitis herpetiformis patients with good response to gluten-free dietary treatment will be recruited.

Enrollment: 23 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Study patients:

• Dermatitis herpetiformis diagnosis
• Dermatitis herpetiformis rash not responding to a strict gluten-free diet after at least 3 years

Control patients:

• Dermatitis herpetiformis diagnosis
• Dermatitis herpetiformis with good response to a gluten-free diet

Exclusion criteria

Study patients:

-Not following strict gluten-free diet

Control patients:

-Not following a strict gluten-free diet

Trial design

23 participants in 2 patient groups

Refractory dermatitis herpetiformis patients

Description:

Dermatitis herpetiformis rash not controlled by strict glute-free diet

Treatment:

Other: Assessment of prognosis of refractory dermatitis herpetiformis. No intervention

Dermatitis herpetiformis patients with good response to gluten-free diet

Description:

Dermatitis herpetiformis rash controlled by strict glute-free diet

Treatment:

Other: Assessment of prognosis of refractory dermatitis herpetiformis. No intervention