Dermatologists' Educational Demonstration for Epiduo Application

Seoul National University

Status: Completed

Conditions: Facial Acne; Local Adverse Effects

Treatments: Drug: Epiduo- once daily, simple instruction for application; Drug: Epiduo once daily with detailed instruction for how to apply it; Drug: BPO once daily

Study type: Interventional

Funder types: Other

Identifiers

NCT02192632

1402-051-555 (Registry Identifier)

ADP-BPO

Details and patient eligibility

About

The purpose of this study is to evaluate the efficacy and tolerability of this combination gel compared with BPO monotherapy in Korean patients, and test clinical practicability of dermatologists' educational demonstration for how to apply this gel in reducing uncomfortable irritations.

Enrollment: 85 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• mild to moderate acne were evaluated by Leeds revised acne grade from 2 to 6
• age: 18-40

Exclusion criteria

• pregnancy
• mental illness
• intake of oral isotretinoin within 6 months
• application of the other oral or topical acne medications
• chemical peeling or light based treatments within 6 weeks.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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85 participants in 3 patient groups, including a placebo group

Epiduo- dermatologist's detailed instruction

Experimental group

Description:

After randomly assigned to side of epiduo application, half of total patients were also re-assigned into detailed instruction for application of epiduo from dermatologist

Treatment:

Drug: Epiduo once daily with detailed instruction for how to apply it

Epiduo- drug insert only gruop

Experimental group

Description:

After randomly assigned to side of epiduo application, half of total patients were also re-assigned into drug insert only group

Treatment:

Drug: Epiduo- once daily, simple instruction for application

BPO group

Placebo Comparator group

Description:

After randomly assigned to side of BPO application, patients apply BPO during 12 week

Treatment:

Drug: BPO once daily