Description Des Troubles Respiratoires Chez Les Patients Suivis Pour Une Sclérose en Plaques (SEP) sévère (RespiMuS)

Institut National de la Santé Et de la Recherche Médicale, France

Status: Completed

Conditions: Respiration Disorders; Multiple Sclerosis

Treatments: Diagnostic Test: Polysomnography

Study type: Interventional

Funder types: Other

Identifiers

NCT03339817

2017-A01845-48 (Registry Identifier)

C16-111

Details and patient eligibility

About

The purpose of this study is to describe respiratory disorders in patients with severe multiple sclerosis (EDSS from 6.5).

Enrollment: 70 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis criteria of multiple sclerosis (MS) fulfilling revised McDonald criteria (2010)
• EDSS score from 6.5
• no relapse during the 3 last months
• Informed consent prior to any study procedure

Exclusion criteria

• Any severe Chronic Obstructive Pulmonary Disease (III or IV)
• Pregnancy or woman with childbearing potential
• contraindication to MRI

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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70 participants in 1 patient group

Patients with severe MS

Other group

Description:

polysomnography and functional pulmonary testings.

Treatment:

Diagnostic Test: Polysomnography