Description of the Uterine Cavity in Patients With Recurrent Miscarriages

H

Hvidovre University Hospital

Status

Completed

Conditions

Habitual Abortions
Recurrent Miscarriages

Treatments

Other: Office hysteroscopy

Study type

Observational

Funder types

Other

Identifiers

NCT02746588
H-15011157

Details and patient eligibility

About

To be diagnosed with recurrent miscarriages, a couple might have a child, however experiences three or more miscarriages, primarily this happens during the first trimester. These miscarriages often needs medical evacuation or a D & C. Surgery or retained tissue increases the risk of complications as infection and/or adhesions, known as asherman syndrome, which may result in subfertility. Recently chronic infection in the endometrium has been proposed to contribute to the condition, as protocols including treatment with antibiotics have led to birth at term for some of these women. Using the very minimal invasive office hysteroscopy, the investigators aim to describe the uterine cavity in patients diagnosed with recurrent miscarriages regarding both abnormalities in the endometrium and chromic infection.

Full description

The Unit for Recurrent Pregnancy-loss at Rigshospitalet treats about 300 of couples with recurrent miscarriages a year. Together with the current examination program, the investigators plan to describe the uterine cavity according to abnormalities as septa, adhesions and further the condition for the endometrium regarding infection and hormone receptors. This description will include descriptive office hysteroscopy with biopsies for histologic - and immunohistochemically examinations.

Enrollment

100 patients

Sex

Female

Ages

18 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Correctly diagnosed with recurrent miscarriages

Exclusion criteria

Known course of the condition

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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