Description of Treatment Patterns and Population Characteristics of Pre-dialysis CKD Patients in the Czech Republic

Value Outcomes

Status: Enrolling

Conditions: Chronic Kidney Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT05380843

NephroSCREEN

Details and patient eligibility

About

The decision making in the Czech nephrology offices depends on the local common practice which is likely to be heterogenous. In other words, the same patient would be indicated to different therapy and regimen at different sites. To date, the practices and treatment paths have not been described. The aim of the present epidemiological research is to characterize the population of CKD patients at the point of treatment choice and to outline the motivation of nephrologist to initiate particular therapy.

Full description

This is epidemiological (observational) cross-sectional survey. Data for the research will be obtained from clinical records and patient´s questionnaires and transcribed into electronic case report forms (eCRF) by physician anonymized using subject ID.

This observational research will not impose any additional procedures, assessments, or changes in addition to the routine management of subjects.

The research does not aim to follow treatment with a single medicinal product. The management of patients will be described in general terms. Names of active substances will be collected rather than the names of individual products.

Enrollment: 1,200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patient of 18 years and older
• Signed consent with processing of personal data as per the GDPR and the applicable national legal requirements
• Chronic kidney disease (CKD) category 4 to 5 characterized by GFR < 30 ml/min/1.73m2 for at least 3 months

Exclusion criteria

• Patients on chronic dialysis
• Patient waiting for kidney transplant
• Patient requiring indication of dialysis (e.g., life-threatening changes in fluid, electrolyte, and acid-base balance, serositis, pruritus, inability to control blood pressure, lethargy or other changes in mental status, symptoms of uraemia, GFR < 10 ml/min/1.73 m2)
• Patient with altered mental state unable to fill patient questionnaires