Desflurane in Children With Laryngeal Mask Airway

Seoul National University

Status: Completed

Conditions: Desflurane Anesthesia

Treatments: Drug: Sevoflurane/Desflurane; Drug: Sevoflurane

Study type: Interventional

Funder types: Other

Identifiers

NCT02470442

H-1504-116-668

Details and patient eligibility

About

The purpose of this study is to characterize the airway responses to desflurane during maintenance of and emergence from anesthesia in children whose airways were supported with laryngeal mask airways (LMAs).

Enrollment: 200 patients

Sex: All

Ages: 2 to 6 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• scheduled for elective surgery under general anesthesia with laryngeal mask airway

Exclusion criteria

• history of reactive airways disease with an acute exacerbation within the past 2 weeks
• if wheezing or an active upper respiratory infection was present on the day of surgery
• if there was a history of malignant hyperthermia
• a history of moderate-to-severe hepatic dysfunction following anesthesia with desflurane not otherwise explained.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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200 participants in 2 patient groups

Sevoflurane/Desflurane

Experimental group

Description:

After induction of general anesthesia with sevoflurane, anesthesia was maintained with desflurane.

Treatment:

Drug: Sevoflurane/Desflurane

Sevoflurane

Experimental group

Description:

the anesthetic induction and maintenance with sevoflurane.

Treatment:

Drug: Sevoflurane