Desogestrel for the Preoperative Treatment of Endometrioma Compared With Placebo

Rajavithi Hospital

Status and phase

Completed

Phase 3

Phase 2

Conditions

Endometrioma

Treatments

Drug: Desogestrel Oral Tablet

Study type

Interventional

Funder types

Other

Identifiers

NCT04941833

147/2564

Details and patient eligibility

About

Use of the oral desogestrel compared with placebo for preoperative treatment of endometrioma in the patient who underwent to surgery in next 3 months The result will be evaluated on cyst diameter, the associated pain and side effect of the oral desogestrel.

Full description

Use of the oral desogestrel compared with placebo for preoperative treatment of endometrioma in the patient who underwent to surgery in next 3 months in Rajvithi hospital Patient will randomized in 2 group : Desogestrel and placebo After 1 months and 3 months the patient have to come to hospital to evaluate the result of study The result will be evaluated on cyst diameter, the associated pain and side effect of the oral desogestrel.

Enrollment

20 patients

Sex

Female

Ages

15 to 49 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Thai female and foreigner who can understand Thai language
Age 15-49 years
Diagnose as endometrioma sized more than 3 cm
Underwent to surgery in next 13 weeks

Exclusion criteria

History of endometriosis
Pregnancy woman
Contraindication for desogestrel : History of thrombotic event, Autoimmune disease,gestational trophoblastic disease
Ovarian endometrioma with complications : Ruptured, twisted
Contraindications for NSAIDs : Peptic ulcer, thrombocytopenia, liver disease
History of hormonal treatment for endometrioma : DMPA,OCP, GNRH agonist/antoginist