DetectAB - Detecting Antibiotics

University Hospital Basel

Status: Completed

Conditions: Antibiotic Drug Concentration in Sweat

Treatments: Diagnostic Test: analysis of last resort antibiotic drug (Flucloxacillin, Imipenem, Vancomycin or Cefepim) in sweat and blood

Study type: Observational

Funder types: Other

Identifiers

NCT03678142

2018-01155 me18Eckstein;

Details and patient eligibility

About

The secretion of different kinds of antibiotic drugs in sweat is investigated. The concentration and pharmacodynamics of antibiotic drugs in sweat and blood will be compared.

Enrollment: 17 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients
• Ability to understand the purpose of the study, provide signed and dated informed consent and qualify for therapeutic drug monitoring
• In-patients receiving intravenous therapy with last resort antibiotics Cefepim, Floxapen, Imipenem or Vancomycin for at least 24 hours
• Glomerular Filtration Rate >/= 50 ml/Min

Exclusion criteria

• Glomerular Filtration Rate < 50 ml/Min