Detecting the Influence of Cataract Surgery on the Development of Diabetic Retinopathy in Patients With Diabetes Mellitus Type 2 With and Without Diabetic Retinopathy Using OCT Angiography

Cairo University (CU)

Status: Unknown

Conditions: Diabetic Retinopathy

Treatments: Device: Phacoemulsification

Study type: Observational

Funder types: Other

Identifiers

NCT03571139

Abeer T Al Hanaineh

Details and patient eligibility

About

Detecting the influence of cataract surgery on the development of diabetic retinopathy in patients with diabetes mellitus type 2 with and without diabetic retinopathy using OCT angiography.

Full description

Patients with diabetes mellitus type 2 with and without without diabetic retinopathy (on biomicroscopy examination) who need cataract surgery, will undergo OCT angiography examination prior to their cataract surgery. Average vessel density (%) in superficial capillary plexus, deep capillary plexus and choriocapillaris, parafoveal vessel density (%) in the superficial and deep plexuses, FAZ area (mm2) in the superficial capillary plexus, FAZ circularity, retinal thickness, microaneurysms and capillary non-perfusion will be taken into analysis.

Patients will be examined on the first day after the cataract surgery with phacoemulsification and in the bag posterior chamber lens implantation.

All patients will undergo OCT angiography examination four weeks after their cataract surgery.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with diabetes mellitus type 2 with and without diabetic retinopathy who needs cataract surgery.
• Patients who need cataract surgery without any intravitreal injections.
• Absence of any ocular disease other than diabetes mellitus.
• Cataract density allowing good visualization of the fundus by OCT angiography.
• Patients with uneventful cataract surgery with phacoemulsification.

Exclusion criteria

• Patients who fail to comply with the follow-up schedule.
• Very dense cataract not allowing good visualization of the fundus by OCT angiography.
• Patients with complicated cataract surgery with phacoemulsification.
• Patients who need cataract surgery with any intravitreal injection.

Trial design

50 participants in 1 patient group

Diabetics type 2 with and without diabetic retinopathy

Description:

Patients with diabetes mellitus type 2 with and without diabetic retinopathy who needs cataract surgery by phacoemulsification. All patients will undergo OCT angiography examination prior to their cataract surgery and 4 weeks after the cataract surgery.

Treatment:

Device: Phacoemulsification