Detection and Biopsy Guidance of Nasopharyngeal Carcinoma Based on Artificial Intelligence and Endoscopic Images

Chinese Academy of Sciences

Status: Enrolling

Conditions: Image-Guided Biopsy; Nasopharyngeal Carcinoma

Treatments: Diagnostic Test: Nasopharyngeal Endoscopy image-guided Biopsy

Study type: Observational

Funder types: Other

Identifiers

NCT05202626

CASMI002

Details and patient eligibility

About

Due to the occult anatomic location of the nasopharynx and frequent presence of adenoid hyperplasia, the positive rate for nasopharyngeal carcinoma identification during biopsy is low, thus leading to delayed or missed diagnosis for nasopharyngeal carcinoma upon initial attempt. Here, we aimed to develop an artificial intelligence tool to detect nasopharyngeal malignancies and guide biopsy under endoscopic examination based on deep learning.

Full description

Due to the occult anatomic location of the nasopharynx and frequent presence of adenoid hyperplasia, the positive rate for nasopharyngeal carcinoma identification during biopsy is low, thus leading to delayed or missed diagnosis for nasopharyngeal carcinoma upon initial attempt. Here, we aimed to develop an artificial intelligence tool to detect nasopharyngeal malignancies and guide biopsy under endoscopic examination based on deep learning.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The patient was found to have a nasopharyngeal lesion through the nasopharyngeal endoscopy and the clinicans considered it necessary to perform an biopsy.
• Hemilateral lesion with limited size.

Exclusion criteria

• Patients with nasopharyngeal cancer, oropharyngeal cancer, hypopharyngeal cancer, etc. who have already been treated.

Trial design

100 participants in 5 patient groups

Sun Yat-Sen University Cancer Center

Description:

The participant who is found to have a nasopharyngeal lesion through the nasopharyngeal endoscopy in Sun Yat-Sen University Cancer Center. The physicians in Sun Yat-Sen University Cancer Center consider it necessary to perform an endoscopic image-guided biopsy.

Treatment:

Diagnostic Test: Nasopharyngeal Endoscopy image-guided Biopsy

Guangdong Provincial People's Hospital

Description:

The participant who is found to have a nasopharyngeal lesion through the nasopharyngeal endoscopy in Guangdong Provincial People's Hospital. The physicians in Guangdong Provincial People's Hospital consider it necessary to perform an endoscopic image-guided biopsy.

Treatment:

Diagnostic Test: Nasopharyngeal Endoscopy image-guided Biopsy

Nanfang Hospital, Southern Medical University

Description:

The participant who is found to have a nasopharyngeal lesion through the nasopharyngeal endoscopy in Nanfang Hospital. The physicians in Nanfang Hospital consider it necessary to perform an endoscopic image-guided biopsy.

Treatment:

Diagnostic Test: Nasopharyngeal Endoscopy image-guided Biopsy

Fujian Provincial Cancer Hospital

Description:

The participant who is found to have a nasopharyngeal lesion through the nasopharyngeal endoscopy in Fujian Provincial Cancer Hospital. The physicians in Fujian Provincial Cancer Hospital consider it necessary to perform an endoscopic image-guided biopsy.

Treatment:

Diagnostic Test: Nasopharyngeal Endoscopy image-guided Biopsy

Hainan Provincial People's Hospital

Description:

The participant who is found to have a nasopharyngeal lesion through the nasopharyngeal endoscopy in Hainan Provincial People's Hospital. The physicians in Hainan Provincial People's Hospital consider it necessary to perform an endoscopic image-guided biopsy.

Treatment:

Diagnostic Test: Nasopharyngeal Endoscopy image-guided Biopsy