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Detection and Treatment of Depression in Patients Admitted to the General Hospital

R

Radboud University Medical Center

Status and phase

Unknown
Phase 2

Conditions

Depression
Depressive Disorder

Treatments

Behavioral: Cognitive Behavioural Therapy

Study type

Interventional

Funder types

Other

Identifiers

NCT00521911
PROJECT9999

Details and patient eligibility

About

Depression is a common disorder among patients with a somatic illness admitted to the general hospital. Patients with depression do worse in terms of their somatic symptoms or functioning that those without depression. They also stay in the hospital for longer.

That is the reason that we are interested to know whether patients with depression do better if their depression is recognised earlier and treated appropriately. We would like to find out which questionnaires are most suitable in clinical practice to help pick up patients with a depression. In addition, we would like to know whether a short-term psychological treatment of depression would be of any help. We hope to be able to show that this treatment would not only result in a reduction of depressive symptoms, but also in a better and quicker recovery of the somatic illness.

The treatment will consist of 6 to 9 weekly sessions of one hour, conducted by a cognitive behavioural assistant. Initially, the treatment will take place in the hospital. When patients are discharged, treatment sessions will continue at home. The treatment will focus on things like recognising and challenging unhelpful thoughts, planning of activities, and testing out of predictions by setting up behavioural experiments. Three monthly booster sessions will be offered to help patients to maintain their gains and prevent relapse. We will reassess the symptoms of the patients at three and six months after the end of treatment.

Enrollment

60 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Depressive Disorder

Exclusion criteria

  • Severe Physical Disfunction
  • Severe Cognitive Disfunction
  • Speech and/or Hearing Disorder
  • Limited knowledge of the Dutch language

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

60 participants in 2 patient groups

1
Active Comparator group
Description:
Cognitive Behavioural Therapy
Treatment:
Behavioral: Cognitive Behavioural Therapy
2
No Intervention group
Description:
Treatment as Usual

Trial contacts and locations

1

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Central trial contact

Matthijs W. Beltman, MSc

Data sourced from clinicaltrials.gov

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