Detection in Peripheral Blood of Circulating Tumor Cells in Patient With Head and Neck Squamous Cell Carcinoma (CTCVADS)

Institut de Cancérologie de Lorraine

Status: Completed

Conditions: Head and Neck Cancer

Treatments: Other: Circulating Tumor Cells

Study type: Interventional

Funder types: Other

Identifiers

NCT02892786

2010-A00586-33

Details and patient eligibility

About

The dissemination of individual tumor cells is a common phenomenon in solid cancers. Detection of tumor cells in peripheral blood circulating tumor cells (CTC) in nonmetastatic situation is of high prognostic significance.

The objective of our study was to detect circulating tumor cells in two different method in patient with head and neck squamous cell carcinoma .

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years
• Patient with head and neck squamous cell cancer stage III or IV histologically proven
• Patient naive to any prior therapy
• Patient with operate cancer and resectable tumor
• Hemoglobin ≥ 10g / dL
• Performance status ≤ 2
• Ability to provide written informed consent
• Patient's legal capacity to consent to study participation

Exclusion criteria

• Other previous histology tumors
• Medical conditions or acute or chronic severe psychiatric disorders
• Deprived of liberty or under supervision

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

experimental

Experimental group

Treatment:

Other: Circulating Tumor Cells