Detection of Area of Ischemia in Patients With Subacute Stroke Via a Hybrid EEG-fNIRS Brain-computer Interface

The University of Texas System (UT)

Status: Terminated

Conditions: Stroke

Treatments: Device: Combined EEG and fNIRS

Study type: Interventional

Funder types: Other

Identifiers

NCT03034902

HSC-MS-16-0481

Details and patient eligibility

About

The purpose of this research study is to determine whether a combined electroencephalography (EEG) and functional near infrared spectroscopy (fNIRS) recording is able to detect changes in brain activity and blood flow after stroke.

Enrollment: 5 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients with a subacute ischemic stroke with symptom onset within 8 weeks
• Must have a measurable deficit on the National Institute of Health Stroke Scale (NIHSS)
• Able to give and sign informed consent

Exclusion criteria

• Aphasia
• Underlying dementia
• Any chronic neurological disorder
• Malignancy
• Non-ambulatory (ambulation with assistance will be included)
• Modified Rankin Score (mRS) > 3

Trial design

Primary purpose: Device Feasibility

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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5 participants in 1 patient group

Combined EEG and fNIRS

Experimental group

Description:

EEG is electroencephalography. fNIRS is functional near infrared spectroscopy. The EEG+NIRS recordings will be obtained via an extended EEG cap that is applied to the subject's head. Changes in neuronal activity and hemodynamics will be measured.

Treatment:

Device: Combined EEG and fNIRS