Detection of Brain Metastasis by MRI in Metastatic Colorectal Cancer Patients

Poitiers University Hospital

Status: Active, not recruiting

Conditions: Metastatic Colon Cancer

Treatments: Device: Magnetic resonance imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT03694938

DEMECIA

Details and patient eligibility

About

The aim of this study is to prospectively determine the incidence of brain metastases in metastatic colorectal cancer patients using systematic annual screening by MRI.

Enrollment: 143 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with histologically proven colorectal adenocarcinoma
• Metastases from colorectal cancer diagnosed since less than 6 months
• Indication of an oncologic treatment

Exclusion criteria

• Patient with contraindication for MRI
• Diagnosis of cancer other than colorectal cancer in the last three years, except in situ cancers, basal-cell skin cancer or squamous-cell skin cancer, and other cancer with low risk of brain dissemination according to the investigator
• Pregnant or breastfeeding women, women of childbearing potential without effective contraception

Trial design

Primary purpose: Screening

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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143 participants in 1 patient group

Magnetic resonance imaging

Experimental group

Description:

Annual MRI during 3 years

Treatment:

Device: Magnetic resonance imaging