Detection of Functioning Pituitary Microadenoma: PET/MRI Versus PET/CT
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About
This is a prospective case-control study to compare the usefulness of 18F-FDG PET/MRI with that of 18F-FDG PET/CT in detection of functioning pituitary microadenomas.A single dose of 370 Mega-Becquerel (MBq) 18F-FDG will be injected intravenously.Visual and semiquantitative method will be used to assess the PET/MRI and PET/CT images.
Full description
Magnetic resonance imaging (MRI) may be insufficient to locate functioning pituitary microadenoma.This study compared the usefulness of 18F-FDG PET/MRI with that of 18F-FDG PET/CT in detection of functioning pituitary microadenomas in patients with inconclusive conventional MRI findings. Trans-sphenoidal adenomectomy was performed within 2 weeks of imaging.The PET/CT and PET/MRI findings and tracer uptake levels were correlated with the surgical findings and pathological results.
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Inclusion criteria
- Patients who were pathologically diagnosed with pituitary adenoma after surgery were recruited, and were able to provide basic information and sign the written informed consent form.
Exclusion criteria
- The exclusion criteria included claustrophobia, kidney or liver failure, and inability to fulfill the study.
Trial design
Primary purpose
Allocation
Interventional model
Masking
100 participants in 1 patient group
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Central trial contact
Hao Wang, PhD
Data sourced from clinicaltrials.gov
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