Detection of Helicobacter Pylori in Ulcerative Colitis Patients

Tanta University

Status: Unknown

Conditions: Inflammatory Bowel Diseases

Treatments: Diagnostic Test: Colonoscopy and biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT03172000

IBD Helicobacter

Details and patient eligibility

About

Helicobacter pylori (H. pylori) infection is one of the most common infectious diseases in humans.

Full description

Several bacterial and viral agents may have a role in the aetiology of IBD. In theory, H. pylori infection could be involved in IBD by inducing alterations in gastric and/or intestinal permeability or by causing immunological derangements resulting in absorption of antigenic material and autoimmunity via various immunological pathways.

Enrollment: 60 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• newly diagnosed ulcerative colitis

Exclusion criteria

• Other diagnosis

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Colonoscopy and biopsy

Active Comparator group

Description:

IBD patients

Treatment:

Diagnostic Test: Colonoscopy and biopsy

Colonoscopic biopsy

No Intervention group

Description:

Non IBD patients colonoscopic biopsy