Detection of Microplastics in Cardiac Surgery Patients

Kun Hua

Status: Not yet enrolling

Conditions: Cardiac Surgery; Microplastics; Nanoplastics; Cardiovascular Diseases

Treatments: Other: Microplastics

Study type: Observational

Funder types: Other

Identifiers

NCT05600010

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Details and patient eligibility

About

The exponential growth in plastic production/use translates into a parallel increase in environmental plastic waste, which is constantly degraded into microplastics and nanoplastics. Information on the effects of microplastics on human health is still preliminary.

Cardiac surgery patients is a population high exposed to plastics. This observational study will obtain biological samples of cardiac surgery patients as a reference and vulnerable group of individuals highly exposed to microplastics and potentially more susceptible.

The objective of this research is to be able to detect microplastics on blood and operation samples of cardiac surgery patients as well as their potential genotoxic and immunological damage.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18 years
• Elective cardiac surgery

Exclusion criteria

• Emergency surgery or limited-term surgery
• Previous cardiac surgery
• Previous severe liver disease
• Pregnant or planning to become pregnant
• Have a malignant tumor

Trial design

40 participants in 1 patient group

Study group

Description:

Detection of microplastics/nanoplastics in heart tissue and the blood of patients undergoing cardiac surgery

Treatment:

Other: Microplastics