Detection of Microplastics in Patients With Periodontitis (micropl_perio)

Sigmund Freud PrivatUniversitat

Status: Not yet enrolling

Conditions: Periodontitis; Periodontal Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT07231198

17538733

SFU

Details and patient eligibility

About

Plastic particles known as microplastics are now a ubiquitous part of the environment. Human exposure to microplastics occurs through the consumption of contaminated food and polluted air, which affect the intestinal system. Several studies have detected the presence of microplastics in various parts of the human digestive system, e.g., in feces. Unfortunately, little is known about the presence of microplastics in the mouth as the primary part of the digestive system. Periodontal pockets can be considered an ideal deposition site for microplastics. Since microplastics are suspected of being an immunomodulatory factor, there is great interest in their presence in subgingival plaque and their possible exacerbation of chronic inflammatory diseases such as periodontitis. The following study aims to clarify the presence, classification, and concentration of microplastics in subgingival plaque. No comparable study has been identified to date.

Enrollment: 25 estimated patients

Sex: All

Ages: 18 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 18 and over

• Gender: Female / male / diverse

• Patients

  • who have been diagnosed with stage III and IV periodontitis.
  • who have not yet started periodontal treatment.
  • who still have at least 20 teeth. Providing written consent to participate in the study.

Exclusion criteria

• Patients

  • who have already been treated for periodontitis
  • who have already undergone/begun periodontitis treatment

Trial design

25 participants in 1 patient group

patients with periodontitis, stage 3 or 4

Description:

Status assessment with supragingival cleaning Sample collection with sterile universal curette (steel) from the bottom of the pockets of the 4 deepest gum pockets (ST \>= 5mm) pooled in ultrapure water