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Detection of Subclinical Enthesitis by Ultrasonography

F

Fatih Sultan Mehmet Training and Research Hospital

Status

Completed

Conditions

Enthesitis

Treatments

Diagnostic Test: Ultrasound

Study type

Observational

Funder types

Other

Identifiers

NCT04209894
karamanlioglu.duygu

Details and patient eligibility

About

Detection of subclinical enthesitis by ultrasonography

Full description

A total of 30 patients with psoriasis and 30 age-matched healthy controls, all without musculoskeletal diseases, will be recruited. They will undergo dermatological assessment and a blinded ultrasound (US) evaluation. Clinical assessment included demographics, severity of psoriasis and musculoskeletal clinical examination. Evaluation consisted of the detection of grey scale (GS) enthesitis and Power Doppler signal in enthesis areas. The Madrid Sonography Enthesitis Index (MASEI) scoring system was used to quantify the extent of sonographic entheseal abnormalities.

Enrollment

61 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Age≥18years
  • Patients with psoriasis without musculoskeletal symptoms
  • Healthy controls
  • No joint involvement and no clinical symptoms and signs of enthesitis and synovitis

Exclusion criteria

  • Have history of gout or arthritis or peripheral neurological disease of lower extremity.
  • Have history of trauma and intensive sport activity in last 2 weeks.
  • Have received any systemic therapy (i.e. DMARD, NSAIDs, corticosteroids, immunosuppressants, retinoids or biological agents) in 3 months
  • Pregnant or breast-feeding

Trial design

61 participants in 2 patient groups

Psoriasis
Description:
They will undergo dermatological assessment and a blinded ultrasound (US) evaluation.
Treatment:
Diagnostic Test: Ultrasound
Control
Description:
They will also undergo dermatological assessment and a blinded ultrasound (US) evaluation.
Treatment:
Diagnostic Test: Ultrasound

Trial contacts and locations

1

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Central trial contact

Feyza Unlu Ozkan, Assoc. Prof.; Duygu Silte Karamanlioglu, MD

Data sourced from clinicaltrials.gov

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