Detection of Ultrasound Contrast Signals in the Cerebral Circulation

University of Nebraska

Status: Withdrawn

Conditions: Coronary Artery Disease; Brain Vascular Disorders

Treatments: Procedure: Ultrasound on Temporal Bone

Study type: Interventional

Funder types: Other

Identifiers

NCT00579241

0113-06-FB

Details and patient eligibility

About

To Determine whether transcranial ultrasound can detect the presence of intravenously injected microbubbles used routinely for dobutamine stress echocardiography.

Full description

The purpose of this study is to determine whether the intravenous microbubbles used to improve border delineation during dobutamine stress echocardiographies (DSE) can be detected within the cerebral circulation.

Sex: All

Ages: 19+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• male or female age >19 years of age
• scheduled for a stress echocardiogram
• negative urine pregnancy test within two hours of ultrasound contrast administration required for females of childbearing age unless post-menopausal or with evidence of surgical sterilization
• be conscious and coherent, and able to communicate effectively with trial personnel

Exclusion criteria

• pregnant or lactation
• life expectancy of less than 2 months or terminally ill
• Known or suspected hypersensitivity to ultrasound contrast agent used for the study
• complicated hemodynamic instability
• Known left main disease

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 1 patient group

1 Transcranial imaging using Doppler Ultrasound

Experimental group

Description:

Transcranial imaging using Doppler ultrasound

Treatment:

Procedure: Ultrasound on Temporal Bone