Determinants of Adherence to Post-stroke/Transient Ischemic Attack Secondary Prevention Treatment: Cohort Study in the Rhône (OBSTACLE)

Civil Hospices of Lyon

Status: Completed

Conditions: Stroke; Transient Ischemic Attack

Treatments: Other: Patients with stroke or transient ischemic attack

Study type: Observational

Funder types: Other

Identifiers

NCT03153020

69HCL17_0037

Details and patient eligibility

About

The effectiveness of emergency management of acute ischemic stroke has improved considerably in recent years with thrombolysis and more recently thrombectomy. This improvement is accompanied by an increase in the number of stroke survivors. One of the major issues for these ever-increasing survivors is the prevention of recurrence. According to data from the 3 French registries, more than 20% of patients have at least one recurrence. Secondary prevention treatment has demonstrated his efficacy to prevent stroke recurrence.

This evolution justifies identifying factors associated with adherence to secondary prevention treatment, measured at 1 year post-stroke / transient ischemic attack (TIA), in patients included in the STROKE 69 cohort.

Enrollment: 633 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consecutive patients treated for a stroke suspicion at the acute phase,
• with symptom onset (the last time the patient was seen without deficit ) less than 24 hours,
• Managed by the Rhône's emergency medical help service (SAMU), in one of the emergency unit or stroke unit of the Rhône area
• Having given their written consent for the extraction of their healthcare consumption data from the Health Insurance databases

Exclusion criteria

• Hemorrhagic stroke,
• Patient institutionalized in the year following the stroke / transient ischemic attack,
• Patient unable to take treatment alone.

Trial design

633 participants in 1 patient group

Cohort of patients with stroke or transient ischemic attack

Description:

The cohort will be constituted of all consecutive patients admitted for a stroke or transient ischemic attack by the Rhône's emergency medical help service (SAMU), or in one of the emergency unit or stroke unit of the Rhône area, and presenting a symptom-onset (the last time the patient was seen without deficit) less than 24 hours.

Treatment:

Other: Patients with stroke or transient ischemic attack