Determinants on Rocuronium Dose for Deep Block in Bariatric Surgery

Seoul National University

Status: Unknown

Conditions: Bariatric Surgery

Treatments: Drug: deep neuromuscular blockade in bariatric surgery

Study type: Observational

Funder types: Other

Identifiers

NCT04709406

B-2009/639-301

Details and patient eligibility

About

Find out the deciding factor(total body weight, corrected body weight, ideal body weight, fat-free mass, body mass index, skeletal muscle mass, body fat) of neuromuscular blocker dose for deep neuromuscular blockade in bariatric surgery.

Full description

Before the surgery, total body weight, corrected body weight, ideal body weight, fat-free mass, body mass index were measured by height and weight and skeletal muscle mass and body fat were measured by Bioelectrical impedance analysis (InbodyH20B). Find the highest correlation between the 8 factors (total body weight, corrected body weight, ideal body weight, fat-free mass, body mass index, skeletal muscle mass, body fat) and the amount of rocuronium administered to deep neuromuscular blockade in bariatric surgery.

Enrollment: 90 estimated patients

Sex: All

Ages: 20 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients aged 20-80 and American Society of Anesthesiology Physical Grade (ASA) I-II, who undergo bariatric surgery

Exclusion criteria

• kidney disease (GFR<60)
• allergy to study drugs
• decline participation
• side effect of propofol and remifentanil
• when anesthesia does not maintain the level of alertness (BIS) below 60 even when the anesthetic dose is increased, or when hemodynamic instability such as bradycardia and hypotension appears

Trial design

90 participants in 1 patient group

obese patients

Description:

obese patients underwent bariatric surgery

Treatment:

Drug: deep neuromuscular blockade in bariatric surgery