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Determination of Blood Tumor Cells

University of Zurich (UZH) logo

University of Zurich (UZH)

Status

Completed

Conditions

Abnormalities Cell Epithelial
Leukemia, Lymphocytic, Chronic, B-Cell

Study type

Observational

Funder types

Other

Identifiers

NCT04290923
2016-01140

Details and patient eligibility

About

Magnetic nanoparticles coated with anti-EpCAM or anti-CD52 antibodies will be tested ex-vivo in patients blood .

Full description

Magnetic nanoparticles, coated with epithelial cell adhesion molecule (EpCAM)-antibodies are designed to interact with epithelial tumor cells. Aim of this study is to see if circulating tumor cells (EpCAM as marker)can be removed out of the blood with the help of these particles. Patients suffering from prostate, colon, lung or pancreatic cancer will be asked to test their blood.

Similarly, magnetic nanoparticles will be coated with antibodies, directed against non-solid tumors in the blood such as lymphoma or leukemia (CD52 as marker).

Enrollment

71 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Epithelial cell cancer, advanced stage Non-solid tumors (lymphoma, leukemia)

Exclusion criteria

Inability to understand the language of the center (German)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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