Determination of Optimum Age for DXA Screening for Osteoporosis in HIV - The Probono 1 Study (Probono1)

King's College London

Status: Completed

Conditions: Osteoporosis; HIV Infection; Fractures

Study type: Observational

Funder types: Other

Identifiers

NCT01669954

RJ1 09/0329

08/H0805/56 (Other Identifier)

Details and patient eligibility

About

The purpose of this study is to determine the bone mineral density in male and female patients with HIV infection according to age groups.

This will enable a practical approach to screening for osteoporosis and the management and prevention of fragility fractures in people with HIV.

In addition, all risk factors commonly associated with fragility fractures and osteoporosis are collected, as is HIV drug history.

Hence, as secondary outcomes, the associations with reduced bone mineral density can be ascertained.

Enrollment: 440 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 18 years or above Not pregnant Able to comply with study observations and procedures Able to give fully informed consent

Exclusion criteria

• Pregnant Less than 18 years of age Unable to comply with study procedures

Trial design

440 participants in 4 patient groups

Controls, females

Description:

Controls who are presumed HIV uninfected, females, aged 18 or above

Controls, males

Description:

Controls presumed HIV uninfected, males, aged 18 or above

HIV infected patients, males

Description:

HIV patients, males, aged 18 or above

HIV patients,

Description:

HIV patients, females, aged 18 or above