Determination of Pronostics Factors for Advanced Thyroid Carcinoma (pT3 pT4 or M1 at Diagnosis)

Civil Hospices of Lyon

Status: Unknown

Conditions: Thyroid Cancer

Treatments: Other: follow up visit

Study type: Interventional

Funder types: Other

Identifiers

NCT02156362

2011.665

Details and patient eligibility

About

It is generally estimated that 5 % of patients with thyroid cancer will develop distant metastases, and most of them had an advanced stage of the disease at presentation. Thirty per cent of them are resistant to radio iodine therapy and are called "refractory". Their long term survival is estimated to be less than 10 %.

The objective of this study is to identify the factors associated with poor outcome in a cohort of patients with advanced thyroid cancer followed during 5 years. Anaplastic and medullary thyroid carcinomas were excluded.

Enrollment: 643 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Man or woman ≥ 18 years.
• Thyroid cancer differentiated from follicular origins (papillary, vesicular or poorly differentiated carcinoma).
• TNM classification: stage pT3 (≥2 cm), or pT4 or M1 at diagnosis.
• Patient after post operative radioiodine therapy.

Exclusion criteria

• Patient who can not be followed during the protocol.
• Patient who does not consent.

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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643 participants in 1 patient group

follow up

Other group

Treatment:

Other: follow up visit