Determination of the Nature of the Endogenous Ligand of TREM-1 and Its Use as a New Diagnostic Biomarker in Sepsis

University Hospital Center (CHU) Dijon Bourgogne

Status: Withdrawn

Conditions: Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT01903668

Ducoroy PHRC IR 2012

Details and patient eligibility

About

Step 1: Identification and characterisation of the TREM1L protein from samples already available characterised at the hospital Central of Nancy Step 2: Study of the isoforms of TREM1L in correlation with the prognosis of sepsis, Step 3: implementation of assay methods for TREM1L (ELISA or SUPRA MS) Step 4: Validation of assays for TREM1L and its isoforms in a larger number of subjects (inclusion of samples from Dijon CHU and Besançon CHU)

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients hospitalised in a Medical Intensive Care unit whatever the reason
• written informed consent obtained

Exclusion criteria

• patients less than 18 years old or under guardianship, persons without national health insurance.