Determining Optimal Post-Stroke Exercise (DOSE)

University of British Columbia

Status: Completed

Conditions: Brain Ischemia; Cerebrovascular Accident; Cerebral Infarction; Stroke; Brain Infarction; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cerebrovascular Disorders; Brain Diseases

Treatments: Behavioral: Stroke Supplementary Program (SSP); Behavioral: Stroke Monitoring Program (SMonP); Behavioral: Stroke Management Program (SMP)

Study type: Interventional

Funder types: Other

Identifiers

NCT01915368

H13-01933

Details and patient eligibility

About

The investigators will conduct a proof-of-concept study to provide preliminary evidence of efficacy of physical exercise dose on ambulatory function in adults undergoing sub-acute stroke rehabilitation.

Full description

Participants admitted for stroke rehabilitation will be randomly assigned to either the Stroke Management Group, Stroke Monitoring Group or Stroke Supplementary Group. All three groups will receive usual care, in addition to the intervention. The Stroke Management Group will be provided with periodic information about their progress in the area of mobility using specialized activity monitors. The Stroke Monitoring Group will be progressed according to customized protocols using feedback from specialized activity monitors. The Stroke Supplementary Group will receive the same as the Stroke Monitoring Group, but will also receive one additional hour of daily (5 times per week) physical exercise

Enrollment: 75 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Have been admitted to a hospital unit for stroke rehabilitation
• Within 10 weeks post-stroke
• 19 years or older
• Are experiencing difficulty walking

Exclusion criteria

• Requires greater than one person assist for transfer or ambulation
• Have uncontrolled medical condition or another serious medication condition in addition to stroke
• Unable to understand or follow directions

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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75 participants in 3 patient groups

Stroke Management Program (SMP)

Active Comparator group

Description:

Participants will have usual care, and in addition, be provided with periodic information about their progress in the area of mobility using specialized activity monitors

Treatment:

Behavioral: Stroke Management Program (SMP)

Stroke Monitoring Program (SMonP)

Experimental group

Description:

Participants will have usual care, and in addition, be progressed according to customized protocols using feedback from specialized activity monitors

Treatment:

Behavioral: Stroke Monitoring Program (SMonP)

Stroke Supplementary Program (SSP)

Experimental group

Description:

Participants will have usual care, and in addition, will receive the same as the Stroke Monitoring Group, and also receive one additional hour of daily (5 times per week) physical exercise

Treatment:

Behavioral: Stroke Supplementary Program (SSP)