Determining the Etiology of Febrile Neutropenia Using the Karius Sequencing-based Infectious Disease Diagnostic Assay

Karius

Status: Completed

Conditions: Infection; Neutropenia

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT02912117

004-CL-01

Details and patient eligibility

About

Prospective, observational study at Stanford University Hospital comparing the Karius Infectious Disease Diagnostic Sequencing Assay to the Final Microbiologic Diagnosis in Patients with Fever and Neutropenia.

Enrollment: 57 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of age
• Are or will be admitted to Stanford University Hospital for fever and neutropenia
• Neutropenia - an absolute neutrophil count of <500 per cubic mm
• Documented fever or report of fever ≥38.3 or ≥38.0 on two episodes separated by at least one hour, resulting in hospitalization for febrile neutropenia

Exclusion criteria

• Inability to understand instructions and comply with study-related procedures
• Any condition that in the opinion of the treating physician will prevent the subject from completing the study