Determining the Safe Dosage of Ascorbic Acid Used in the Treatment of Occluded Totally Implanted Central Venous Catheter

University of Sao Paulo

Status and phase

Completed

Phase 2

Conditions

Occluded Totally Implanted Central Venous Catheter

Treatments

Drug: Ascorbic Acid

Study type

Interventional

Funder types

Other

Identifiers

NCT01270152

0925-0586

Details and patient eligibility

About

The hypothesis of the study is to evaluate whether ascorbic acid is able to clear totally implanted central venous catheter

Full description

Totally implanted catheter is often occluded and thrombolytic drugs are usually used to restore permeability. In Brazil, the ascorbic acid has been used successfully by a service specialist in cancer treatment. However, no literature on international research that evaluates the efficacy and safety of this procedure. That was why it was decided to develop this research.

Enrollment

21 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Diagnosis of partial or complete obstruction of the totally implanted central venous catheter;
No signs of inflammation in the area of the port.

Exclusion criteria

Use of oral anticoagulants or intravenous administration in the last seven days;
Diagnostic and / or suspected infection in the totally implanted central venous catheter;
Rupture, displacement or fissure of the totally implanted central venous catheter;
Presence of thrombosis in the vein where the catheter is inserted.