Develop a Novel Occupational Training Program for Schizophrenia Patients Based on Virtual Reality Techniques

National Taiwan University

Status: Enrolling

Conditions: Cognitive Impairment; Schizophrenia

Treatments: Behavioral: VR-assisted occupational training

Study type: Interventional

Funder types: Other

Identifiers

NCT05830903

201904105RINB

Details and patient eligibility

About

Establish a novel vocational training program and test its validity in a pilot study.

Full description

40 schizophrenia patients will be recruited to join the virtual reality based vocational training program, the training effect will be compared by interview skills and problem solving before and after the training.

Enrollment: 40 estimated patients

Sex: All

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Having a diagnosis of schizophrenia based on the Diagnostic and Statistical Manual of Mental Disorders -5th version
• Aged between 20 and 55 years.
• Motivated to have a job.
• Having a full-scale IQ > 70 on the Wechsler Adult Intelligence Scale-version IV.
• Having a PANSS positive scale < 70, indicating a stable condition during the illness course.

Exclusion criteria

• Comorbid with other major psychiatric disorders (i.e., bipolar disorders) or neurological diseases.
• Substance abuse within one year.
• Visual impairment and/or hearing impairment that would preclude participation in the VR-based training program.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Sequential Assignment

Masking: None (Open label)

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40 participants in 4 patient groups

Mild ED/NS

Experimental group

Description:

10 patients with mild or none executive function impairment and mild or none negative symptoms.

Treatment:

Behavioral: VR-assisted occupational training

Mild ED/Severe NS

Experimental group

Description:

10 patients with mild or none executive function impairment and severe or moderate negative symptoms.

Treatment:

Behavioral: VR-assisted occupational training

Severe ED/Mild NS

Experimental group

Description:

10 patients with severe or moderate executive function impairment and mild or none negative symptoms.

Treatment:

Behavioral: VR-assisted occupational training

Severe ED/NS

Experimental group

Description:

10 patients with severe or moderate executive function impairment and severe or moderate negative symptoms.

Treatment:

Behavioral: VR-assisted occupational training