Developing a Model to Predict Inpatient Hypoglycemic Episodes

Wake Forest University (WFU)

Status: Withdrawn

Conditions: Hypoglycemic Events; Hyperglycemic Therapy

Treatments: Diagnostic Test: EndoTool; Other: glucose management team; Other: standard of care glucose management

Study type: Interventional

Funder types: Other

Identifiers

NCT05989256

IRB00079298

Details and patient eligibility

About

This study will create a new model to predict hypoglycemic events in diabetic inpatients on anti-hyperglycemic therapy using retrospective data with the goal of developing a model that will accurately predict hypoglycemic episodes in the patient population - piloting the risk score that was developed in the context of EndoTool being rolled out at the institution, to determine the feasibility and acceptability of viewing the risk score in the Electronic Health Record

Full description

Design a model to predict hypoglycemic episodes in real time, rather than retrospectively identifying high risk patients who experienced a hypoglycemic event at some point during their hospitalization, as has been done prior. Potential predictors of hypoglycemia identified in prior work and additional predictors identified by the clinical team to develop a discrete-time multinomial logistic regression model to predict hypoglycemic events in real time. The risk score then will be piloted in the context of our institution's EndoTool Subcutaneous implementation determine the feasibility and acceptability of viewing the risk score in the Electronic Health Record

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Providers taking care of adult patients (18 years and older) on the selected medical floors who are receiving anti-hyperglycemic medications on the chosen services (EndoTool and risk score implementation) and comparison groups (one group with EndoTool implementation and the other group without EndoTool implementation)

Exclusion criteria

• Providers not on the chosen services

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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0 participants in 3 patient groups

experimental hypoglycemia risk score is applied on a service which has already implemented EndoTool

Experimental group

Description:

Service where the experimental hypoglycemia risk score is applied on a service which has already implemented EndoTool

Treatment:

Diagnostic Test: EndoTool

Service where EndoTool is applied without the experimental hypoglycemia risk score

Active Comparator group

Description:

Service where EndoTool is applied without our experimental hypoglycemia risk score

Treatment:

Other: glucose management team

Standard of care glucose management

Active Comparator group

Description:

Service which has not yet implemented EndoTool - providers adjusting insulin and consulting the Glucose Management Team at their discretion

Treatment:

Other: standard of care glucose management